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In both conditions, it has shown remarkable effectiveness, with the added benefit of lowering the risk for heart attack and stroke
(Present-day weight-loss drugs work on just one or two hunger-related hormones.) One particular triple agonist, called retatrutide, has recently been shown in clinical trials to help people with severe obesity shed almost 30 percent of their body weight after about 48 weeks
hence, GLP-1 agonists could be started in primary or secondary care
The systemic iron-regulatory proteins hepcidin and ferroportin are reduced in the brain in Alzheimer's disease
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